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500 Blvd Cartier W, Laval, QC, Canada H7V 5B7

+1 (579) 679-9717

About us

BioVexLab Solutions is a biotechnology company dedicated to advancing the science and applications of extracellular vesicles (EVs). We specialize in the isolation, purification, characterization, and functional evaluation of extracellular vesicles derived from human, bacterial, and plant sources.

Our mission is to bridge cutting-edge EV science with real-world biomedical and biotechnological applications. By combining scientific expertise, advanced analytical technologies, and a rigorous approach to quality and reproducibility, we help researchers and innovators generate reliable data, accelerate discovery, and translate emerging EV technologies into meaningful applications.

From fundamental research and biomarker discovery to drug delivery, therapeutic development, and next-generation biotechnology, BioVexLab Solutions provides specialized expertise and tailored solutions designed to address the evolving needs of the extracellular vesicle field.

We work in close collaboration with academic institutions, biotechnology companies, research organizations, and clinical programs, serving as a trusted scientific and technological partner throughout the EV research and development journey.


Our Mission

At BioVexLab Solutions, our mission is to advance extracellular vesicle science through rigorous, innovative, and reliable technologies.

We provide specialized solutions for the isolation, characterization, and biological evaluation of nanoscale vesicles across diverse biological systems. Our approach is built on scientific rigor, technological excellence, and a commitment to reproducibility, enabling our partners to better understand EV biology and unlock their potential for biomedical and biotechnological applications.

By integrating complementary technologies and multidisciplinary expertise, we aim to accelerate the transition from scientific discovery to innovation.


Our Expertise

Comprehensive EV Characterization Through Complementary Technologies

Understanding extracellular vesicles requires more than a single analytical measurement. At BioVexLab Solutions, we combine complementary technologies and scientific expertise to provide a comprehensive view of EV populations and their key characteristics.

Our analytical capabilities include:

  • Nanoparticle Tracking Analysis (NTA) - for particle concentration and size distribution
  • NanoFCM - for high-resolution analysis of nanoscale particles and EV populations
  • Zeta Potential Analysis - for evaluating surface charge and physicochemical properties
  • Transmission Electron Microscopy (TEM) - for morphological assessment and structural visualization
  • Fluorescence-Based EV Detection -for the detection and characterization of specific vesicle populations
  • Protein and Biomarker Profiling - for molecular characterization and biological investigation

By integrating multiple complementary analytical approaches, we help reduce method-specific bias and provide a more comprehensive understanding of extracellular vesicle populations.

Our technology-driven approach supports robust characterization, reliable data generation, and informed decision-making across the EV research and development pipeline.

Advancing the Potential of Extracellular Vesicles

Extracellular vesicles represent a rapidly evolving field with significant potential across biomedical research, diagnostics, therapeutics, drug delivery, and biotechnology.

At BioVexLab Solutions, we are committed to contributing to this emerging ecosystem by providing the scientific expertise, technological capabilities, and collaborative approach required to move EV innovation forward.


Our Founders

BioVexLab Solutions was founded by Prof. Charles Ramassamy and Dr. Mohamed Haddad, two scientists with complementary expertise and a shared commitment to advancing extracellular vesicle research and innovation.

Prof. Charles Ramassamy, Co-Founder, Scientific & Strategic Director, is an experienced biomedical researcher with extensive expertise in molecular mechanisms, neurodegenerative diseases, biomarkers, and translational research. His scientific leadership and multidisciplinary research background contribute to the development of innovative strategies for understanding complex biological systems and advancing extracellular vesicle research toward clinically relevant applications.

Dr. Mohamed Haddad, Co-Founder, Scientific Innovation & Technology Leader, specializes in extracellular vesicle technologies, including EV isolation, purification, characterization, and analytical methodologies. His expertise spans multiple EV sources and advanced analytical platforms, with a particular focus on developing robust workflows and innovative approaches that support the translation of EV research into practical biomedical and biotechnological applications.

Together, the founders bring together complementary strengths in biomedical science, extracellular vesicle technology, analytical characterization, and translational innovation.

Their shared vision is to establish BioVexLab Solutions as a trusted partner for researchers and innovators seeking to advance extracellular vesicle science, from fundamental discovery and analytical characterization to the development of next-generation EV-based technologies and applications.


From scientific discovery to real world-impact, we transform extracellular vesicle science into innovative solutions and next-generation biomedical applications


 

Advancing your research with tailored solutions

At BioVexLab Solutions, we combine scientific expertise with advanced analytical technologies to provide high-quality extracellular vesicles data suitable for high-impact research and translational applications.

Our services include:

✔ Personalized EVs isolation and characterization workflows
✔ Multi-platform analytical validation
✔ High reproducibility and quality control
✔ Support for academic and industrial research projects
✔ Rapid project turnaround
✔ Dedicated scientific consultation


Our extracellular vesicle analytical services support a broad range of biomedical and biotechnological research areas.

  • Biomarker discovery and liquid biopsy
  • Microbiome and bacterial vesicles studies
  • Plant-derived nanovesicle research
  • Outer Membrane vesicles
  • Neurodegenerative disease research
  • Regenerative medicine and stem cell therapy
  • Drug delivery and nanotherapeutics
  • Aging and oxidative stress research


BioVexLab Solutions collaborates with:

  • Academic research laboratories
  • Biotechnology companies
  • Pharmaceutical developers
  • Clinical research teams

We work closely with partners to design optimized analytical strategies adapted to their scientific objectives and experimental challenges.

Services                                                                              

BioVexLab Solutions delivers integrated analytical workflows spanning the entire extracellular vesicle research pipeline from isolation and characterization to molecular profiling and functional studies. Every project is customized based on sample origin, biological questions, and experimental goals.

Extracellular vesicles isolation

BioVexLab Solutions offers specialized isolation and purification services for extracellular vesicles derived from diverse biological sources including plasma, serum, urine, saliva, cerebrospinal fluid, cell culture media, bacterial cultures, plant extracts, and fruit juices.

Characterization and quantification

BioVexLab Solutions provides comprehensive EVs characterization using advanced analytical technologies.

Parameters measured include:

  • particle size distribution
  • particle concentration
  • vesicle heterogeneity
  • surface charge
  • purity assessment


Analytical technologies used:

  • Nanoparticle Tracking Analysis (NS300 / NTA Pro)
  • Zetasizer for zeta potential and polydispersity index
  • Transmission Electron Microscopy (TEM)
  • Immunogold TEM
  • JESS Western Blot
  • ELISA and NanoFCM

Molecular profiling and biomarker discovery

BioVexLab Solutions offers molecular profiling services to investigate the biological cargo of extracellular vesicles.

Our available analyses include:

  • Total protein quantification (BCA assay)
  • RNA extraction and sequencing
  • Multiplex cytokine quantification (Luminex)
  • Identification of EV-associated target proteins
  • Targeted EV isolation from patient biofluids
  • Candidate biomarker identification (proteins, cytokines, nucleic acids)
  • Custom immunoassay development
  • Integration with patient stratification and therapeutic monitoring

Functional studies

BioVexLab Solutions performs functional studies to investigate the biological activity of extracellular vesicles.

Assays include:

  • Fluorescent EVs labeling and tracking
  • Cellular uptake and internalization studies
  • Cytotoxicity and metabolic activity assays
  • Oxidative stress and ROS assays
  • Cytokine response quantification
  • In vivo biodistribution and toxicity studies

Bacteria-derived EVs research

BioVexLab Solutions investigates extracellular vesicles derived from microbial systems.

Services include:

  • OMVs and BEVs isolation from bacterial cultures
  • Characterization of vesicle-associated virulence factors
  • Host-pathogen interaction studies
  • Cytokine response and barrier permeability assays

Applications include vaccine development, microbiome biomarker discovery, and antimicrobial research.

Plant-derived EVs research

Plant-derived extracellular vesicles represent an emerging platform for biotechnology and therapeutics.

Our services include:

  • Isolation and quantification of plant EVs from juices and extracts
  • Antioxidant activity evaluation
  • Anti-inflammatory and anti-aging assessments

Applications include dermatology and cosmeceutical development.

Publications

BioVexLab Solutions contributes to scientific advancement through collaborative research and analytical support.


Our goal is to generate high-quality EVs data suitable for high-impact scientific publication.


Hight-impact scientific publications related to our expertise


1-A potential multimodal biomarker - cognitive signature associated with the conversion from subjective cognitive decline to mild cognitive impairment.

Haddad M, Ben Khedher MR, Ouechtati C, Fülöp T; Consortium for the early identification of Alzheimer's disease‐Quebec (CIMA‐Q); Ramassamy C. Alzheimers Dement (N Y). 2026 Apr 11;12:e70240. doi: 10.1002/trc2.70240. eCollection 2026 Apr-Jun. PMID: 41970527


2-Exploring the potential of plasma and adipose mesenchymal stem cell-derived extracellular vesicles as novel platforms for neuroinflammation therapy.

Silva RO, Haddad M, Counil H, Zaouter C, Patten SA, Fulop T, Ramassamy C. J Control Release. 2025 Jan 10;377:880-898. doi: 10.1016/j.jconrel.2024.11.060. Epub 2024 Dec 7. PMID: 39617173


3- Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation.

Counil H, Silva RO, Rabanel JM, Zaouter C, Haddad M, Ben Khedher MR, Brambilla D, Fülöp T, Patten SA, Ramassamy C. J Extracell Biol. 2025 Jan 17;4(1):e70027. doi: 10.1002/jex2.70027. eCollection 2025 Jan. PMID: 39830834


4-Donepezil-Loaded Nanocarriers for the Treatment of Alzheimer's Disease: Superior Efficacy of Extracellular Vesicles Over Polymeric Nanoparticles.

Oliveira Silva R, Counil H, Rabanel JM, Haddad M, Zaouter C, Ben Khedher MR, Patten SA, Ramassamy C. Int J Nanomedicine. 2024 Feb 1;19:1077-1096. doi: 10.2147/IJN.S449227. eCollection 2024. PMID: 38317848


5-Implication of Circulating Extracellular Vesicles-Bound Amyloid-β42 Oligomers in the Progression of Alzheimer's Disease.

Ben Khedher MR, Haddad M, Fulop T, Laurin D, Ramassamy C. J Alzheimers Dis. 2023;96(2):813-825. doi: 10.3233/JAD-230823. PMID: 37840502


6-Effect of APOE ε4 allele on levels of apolipoproteins E, J, and D, and redox signature in circulating extracellular vesicles from cognitively impaired with no dementia participants converted to Alzheimer's disease.

Ben Khedher MR, Haddad M, Laurin D, Ramassamy C. Alzheimers Dement (Amst). 2021 Sep 14;13(1):e12231. doi: 10.1002/dad2.12231. eCollection 2021. PMID: 34541286


7-Glutathione: An Old and Small Molecule with Great Functions and New Applications in the Brain and in Alzheimer's Disease.

Haddad M, Hervé V, Ben Khedher MR, Rabanel JM, Ramassamy C. Antioxid Redox Signal. 2021 Aug 1;35(4):270-292. doi: 10.1089/ars.2020.8129. Epub 2021 May 25. PMID: 33637005


8-Apolipoprotein E4-driven effects on inflammatory and neurotrophic factors in peripheral extracellular vesicles from cognitively impaired, no dementia participants who converted to Alzheimer's disease.

Ben Khedher MR, Haddad M, Laurin D, Ramassamy C. Alzheimers Dement (N Y). 2021 Jan 28;7(1):e12124. doi: 10.1002/trc2.12124. eCollection 2021. PMID: 33537405


9-Levels of Receptor for Advanced Glycation End Products and Glyoxalase-1 in the Total Circulating Extracellular Vesicles from Mild Cognitive Impairment and Different Stages of Alzheimer's Disease Patients.

Haddad M, Perrotte M, Ben Khedher MR, Madec E, Lepage A, Fülöp T, Ramassamy C. J Alzheimers Dis. 2021;84(1):227-237. doi: 10.3233/JAD-210441. PMID: 34487040


10-Profile of pathogenic proteins in total circulating extracellular vesicles in mild cognitive impairment and during the progression of Alzheimer's disease.

Perrotte M, Haddad M, Le Page A, Frost EH, Fulöp T, Ramassamy C. Neurobiol Aging. 2020 Feb;86:102-111. doi: 10.1016/j.neurobiolaging.2019.10.010. Epub 2019 Nov 15. PMID: 31883770


11-Methylglyoxal and Glyoxal as Potential Peripheral Markers for MCI Diagnosis and Their Effects on the Expression of Neurotrophic, Inflammatory and Neurodegenerative Factors in Neurons and in Neuronal Derived-Extracellular Vesicles.

Haddad M, Perrotte M, Khedher MRB, Demongin C, Lepage A, Fülöp T, Ramassamy C. Int J Mol Sci. 2019 Oct 3;20(19):4906. doi: 10.3390/ijms20194906. PMID: 31623327


12-Circulating and Extracellular Vesicles Levels of N-(1-Carboxymethyl)-L-Lysine (CML) Differentiate Early to Moderate Alzheimer's Disease.

Haddad M, Perrotte M, Landri S, Lepage A, Fülöp T, Ramassamy C. J Alzheimers Dis. 2019;69(3):751-762. doi: 10.3233/JAD-181272. PMID: 31127773

Contact us

BioVexLab Solutions welcomes collaboration requests, service inquiries, and research partnerships.

Contact our team to discuss your research project and receive a customized analytical proposal.

Email:
info@biovexlab.ca

Forms:

  • Request a Quote
  • Research Partnership Inquiry

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